Welcome to the
Zhou Lab
@ Johns Hopkins University
1. Liu C-M, Wang R-Y, Saijilafu and Zhou F-Q (2013) microRNA-138 and SIRT1 form a mutual negative feedback loop to regulate axon regeneration. (in revision)
2. Saijilafu, Hur E-M, Liu C-M, Xu W-L, and Zhou F-Q (2013) PI3K-GSK3 pathway regulates mammalian axon regeneration by induction of Smad1. (in revision)
3. Saijilafu, Zhang B-Y, and Zhou F-Q (2013) Signlaing pathways regulating axon regeneration. Neuroscience Bulletin (in press)
4. Byun J, Kim BT, Kim YT, HurE-M, and Zhou F-Q (2012) Slit2 inactivates GSK3beta to signal neurite outgrowth inhibition. PLoS One, 7(12):e51895. [Link]
5. Saijilafu and Zhou F-Q (2012) Genetic study of axon regeneration with cultured adult dorsal root ganglion neurons. Journal of Visualized Experiments (JoVE), (66): e4141. [Link]
6. Liu C-M, Hur E-M, and Zhou F-Q (2012) Coordinating gene expression and local axon assembly to control axon growth: potential role of GSK3 signaling. Frontiers in Molecular Neuroscience, 5:3. [Link]
7. Hur E-M, Saijilafu, and Zhou F-Q (2012) Growing the growth cone: remoldering the cytoskeleton to promote axon regeneration. Trends in Neurosciences, 35:3. (Cover featured article) [Link]
8. Kim YT, Hur E-M, Snider WD, and Zhou F-Q (2011) Role of GSK3 signaling in neuronal morphogenesis. Frontiers in Molecular Neuroscience, 4:48. [Link]
9. Saijilafu, Hur E-M, and Zhou F-Q (2011) Genetic dissection of axon regeneration via in vivo electroporation of adult mouse sensory neurons. Nature Communications, 2:543. [Link]
10. Hur E-M, Saijilafu, Lee B-D, Kim SJ, Xu W-L, and Zhou F-Q (2011) GSK3 controls axon growth via CLASP - mediated regulation of growth cone microtubules. Genes & Development, 25(18): 1968-81. [Link]
11. Hur E-M, Yang IH, Kim D-H, Byun J, Saijilafu, Xu W-L, Nicovich RP, Cheong R, Levchenko A, Thakor N, and Zhou F-Q (2011) Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules. PNAS, 108(12): 5057-62. [Link]
12. Hur E-M and Zhou F-Q (2010) GSK3 signaling in neural devleopment. Nature Reviews Neuroscience, 11(8): 539-551. (featured article) [Link]
13. Dill J, Wang H, Zhou F-Q and Li S. (2008) Inactivation of Glycogen Synthase Kinase 3 promotes axonal growth and recovery in the CNS. Journal of Neuroscience, 28(36):8914-28. [Link]
2001-2006
Kim W-Y, Zhou F-Q, Zhou J, Yokota Y, Wang Y-M, Yoshimura T, Kaibuchi K,Woodgett JR, Anton ES, and Snider WD. (2006) Essential roles for GSK-3s in Neurotrophin-induced and hippocampal axon growth. Neuron, 52(6): 981-996[PDF]
Zhou F-Q and Snider WD. (2006) Intracellular control of developmental and regenerative axon growth. Phil. Trans. R. Soc B, 361(1473): 1575-92. [PDF]
Zhou F-Q, Walzer MA, Wu Y-H, Zhou J, Dedhar S, and Snider WD. (2006) NGF supports regenerative axon assembly over CSPGs via an ECM-integrin independent mechanism. Journal of Cell Science, 119: 2787-2796. (Cover image) [PDF]
Zhou F-Q and Snider WD. (2005) GSK-3beta and microtubule assembly in axons. Science, 308: 211-214. [PDF]
Zhou F-Q, Walzer MA and Snider WD. (2004) Turning on the machine: genetic control of axon regeneration by c-Jun. Neuron, 43(1):1-2.
Zhou F-Q, Zhou J, Dedhar S, Wu Y-H, and Snider WD. (2004) NGF-induced axon growth is mediated by localized inactivation of GSK-3β and functions of the microtubule plus end binding protein, APC. Neuron, 42(6): 897-91. (Highlighted article with preview
) [PDF]
Zhou F-Q, Cohan CS. (2004) How actin filaments and microtubules steer growth cones to their targets. Journal of Neurobiology, 58(1): 84-91. [PDF]
Zhou F-Q, Zhong J, and Snider WD. (2003) Extracellular crosstalk: when GDNF meets N-CAM. Cell, 113 (7): 814-815. [PDF]
Cohan CS, Karnes JL and Zhou F-Q. (2003) Culturing neurons from the snail Helisoma. Methods Cell Biol., 71:157-70.
Sinder WD, Zhou F-Q, Zhong J, and Markus A. (2002) Signaling the pathway to regeneration. Neuron, 35 (1): 13-16. [PDF]
Zhou F-Q, Waterman-Storer CM, and Cohan CS. (2002) Focal loss of actin bundles causes microtubule redistribution and growth cone turning. Journal of Cell Biology, 157 (5): 839-849. (Cover image and highlighted article
) [PDF]
Zhou F-Q and Cohan CS. (2001) Growth cone collapse through coincident loss of actin bundles and leading edge actin without actin depolymerization. Journal of Cell Biology, 153(5): 1071-1084. [PDF]